In "To Run, Or Not To Run", little Hamlet is on his way to the pit of death, constantly considering if he should really die or rather live on. Meanwhile, the forces of live try to convince Hamlet to live by throwing candy and underwear at him; and a ton of slowing sleeping pills for good measure.
Player 1 controls Hamlet, trying to avoid the temptations of life, while Player 2 throws said temptations at him. Player 1 wins if Hamlet dies by reaching the pit of death before his will to die runs out; or by a sleeping pill overdose. Player 2 wins if Hamlet decides to live on as his will to die runs out, either because Player 2 feeds him enough candy and underwear, or because he does not reach the pit of death while being slowed from pills.